‘ManningCast’ revels in Heidi Gardner heartbreak during Patrick Mahomes pick-six


Heidi Gardner, a die-hard Chiefs fan, was in disbelief when Kansas City quarterback Patrick Mahomes threw a 99-yard pick-six, resulting in a 21-14 Jaguars lead in their “Monday Night Football” matchup.

During an appearance on ESPN’s “ManningCast,” the “Saturday Night Live” comedian — whose contract was not renewed for Season 51 — didn’t sugarcoat her heartbreak while sobbing to hosts and brothers, Eli Manning and Payton Manning, after the third-quarter blunder.

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“The pass to JuJu — no!” Gardner shouted as she put her hands on her head. “No, no, no, not that!”

The Mannings were cracking up over Gardner’s heartbreak before they replayed her reaction on the broadcast.

Gardner, who was sporting a red Chiefs sweatshirt, couldn’t help but laugh at herself.

Heidi Gardner appeared on ESPN’s “ManningCast” for the Jaguars-Chiefs game on “Monday Night Football” on October 6, 2025. Instagram/Heidi Gardner
Heidi Gardner, a diehard Chiefs fans, was in disbelief when KC quarterback Patrick Mahomes threw a 99-yard pick-six, resulting in a 21-14 Jaguars lead in their “Monday Night Football” matchup on October 6, 2025. Instagram/Heidi Gardner

“He ran all the yards,” she said, referring to linebacker Devin Lloyd, who picked off a Mahomes pass meant for Chiefs wideout JuJu Smith-Schuster and took it to the house to set up a Jaguars’ 31-28 win

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It was Lloyd’s league-best fourth interception of the season after he was named the AFC defensive player of the month for September.

Heidi Gardner reacts to Patrick Mahomes’ pick-six on “Monday Night Football” in a loss to the Jaguars. Instagram/Heidi Gardner

“Had the best time on Manningcast, thank you @ohamaproductions you really caught me in my natural state,” Gardner wrote on her Instagram Story, including a snapshot of her reaction.

Mahomes threw for over 300 yards and was the team’s leading rusher with 60 yards on the ground. He passed for a touchdown and ran one in.

Patrick Mahomes #15 of the Kansas City Chiefs looks on before the game against the Jacksonville Jaguars at EverBank Stadium on October 6, 2025 in Jacksonville, Florida. Getty Images

Jaguars quarterback Trevor Lawrence had a stellar showing, highlighted by a go-ahead touchdown in the final seconds of the game at EverBank Stadium in Jacksonville.

Lawrence, who celebrated his 26th birthday, completed 18 of 25 passes for 221 yards, and also ran for a team-high 54 yards. He had two turnovers.

The Chiefs (2-3) host Detroit (4-1) on Sunday night.


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