49ers vs. Eagles prediction: Wild Card picks, odds, best bets for NFL playoffs


The San Francisco 49ers head to Philadelphia to face the Eagles in one of the best NFL playoff games of Wild Card Weekend.

The reigning champions are seeking to make it back to the promise land and win back-to-back championships while the Niners are hoping to play a home game in the Super Bowl.

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The elements could be a factor in this game with rain showers and flurries in the forecast between 5 p.m. and 6 p.m. in Philadelphia and wind gusts up to 37 mph.

The Eagles are 6-point favorites at home with the Over/Under listed at 44.5.

49ers vs. Eagles odds, prediction

The Niners were a win away from the No. 1 seed in the NFC, and prior to their loss to the Seahawks in the last game of the regular season, they were on a roll.

One of the reasons they were unable to beat the Seahawks was that Christian McCaffrey couldn’t haul in a catch with the 49ers down 10 points on the verge of scoring in the red zone.


Christian McCaffrey #23 of the San Francisco 49ers.
Christian McCaffrey #23 of the San Francisco 49ers. Getty Images

Instead, the ball bounced off McCaffrey’s hands and into the waiting arms of linebacker Drake Thomas. You can expect McCaffrey, who had season lows in rushing attempts and rushing yards, and failed to score for just the fifth time this season, to be fully locked in for this game.

I love McCaffrey’s matchup here against an Eagles defense that allowed 124.4 rushing yards per game this season (11th-most in the NFL) and 17 total touchdowns to running backs (10th-most in the league).

The Eagles don’t blitz much, they rank near the bottom of the league in blitz percentage, but they QB knockdowns per pass attempts, so Purdy will need to get the ball out quickly. McCaffrey should have plenty of opportunities to be effective in the passing game while getting his touches on the ground.


Betting on the NFL?


I’m going heavy on CMC in this game and betting his rushing plus receiving yards prop Over 120 yards, a number he’s topped 10 times this season.

I also think a small play on McCaffrey to score two touchdowns is worth a look at +475.

The Pick: Christian McCaffrey Over 120 rushing + receiving yards (+116, DraftKings)


Why Trust New York Post Betting

Malik Smith has been immersed in the sports betting industry since 2017. He’s a data nerd with a particular focus on the NBA and combat sports. He spends his weeknights in the winter looking for edges on plus-money NBA player props.


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